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Gilead and Glympse Bio Announce Strategicβ ¥≥ Collaboration for U™≠πse of Biomarker Technology in NASH Clinical Develφ"δopment
2019-10-30

Gilead and Glympse Bio Announce Strateg↓♣  ic Collaboration for Use of Biomarke♥ λΩr Technology in NASH Clinical Devel&♣opment

TUESDAY, OCTOBER 29, 2019

Gilead Sciences Inc. and Glympse®↕✘§ Bio, Inc., today annoα≥unced that the companies have entered intoε  a strategic collaboration in♣↕ nonalcoholic steatoh≠♦λ↓epatitis (NASH) clini¥→cal development. Glympse Bio÷✔‌$’s proprietary synthetic biomarkers – bio↕♣engineered to identify stage and progression o✔•≥f disease as well as φ÷early detection of treatment respons€ €e – will be used to determine clinical trial pa♣₽"÷rticipants’ stage of disease at initiaλ÷δ☆l screening and to deφ÷≈©termine responses to study treatmeπ≥nt in Gilead’s NASH clinical program.

“We are excited about the oppδ∞ ortunity to partner with Glympse Bio to h'♣≤§elp inform our NASH development program,” said M¥‌ani Subramanian, MD, PhD €•Senior Vice President, Liver Diseases, Gil₽→♥ead Sciences. “By utilizin&"×Ωg this innovative technolog£"↓y, we hope to better characterize this complex d★₩isease and improve our understanding of how our c₹πompounds impact disease progress♠≤® ion.”

Glympse Bio’s proprietary t→π≈✘echnology, Glympse Inside™, combines syntheti€ αβc biomarkers with machine learning app‍→roaches to identify the stage and mon↕€itor progression of important, complex disease☆•s such as cancer, fibrosis, inflammation,→  and infections, in re÷★al time.

“We are very excited about partnerin∞★∑g with Gilead, a leader in drug deve®≥∏•lopment, to help drive earlieε↕r and more favorable ou¥ tcomes for patients,” said Carol>♠ε×ine J Loew, President ‍↑αand CEO, Glympse Bio.λ✘'≈ “Gilead’s commitment to developing innov<β☆ ative medicines in areas of hiγ✔× gh unmet medical need aligns with our mission oε♠f transforming disease det♣≤↔ection and measuring treatment response, al≈'≈l with the goal of helping improve≥₽≤₩ the lives of patients.”

information source:pharma focus Asia

The original link:https:https:https:/≤≈/www.pharmafocusasia.com/news/gilead-an <∑→d-glympse-bio-announce-str∞☆®ategic-collaboration-for-use-of-biom☆∑arker-technology-in-nash-clinical-developmen ≥↑±t

2019 Asia-pacific pharma IP Leader €£Summit:http://en.zenseegroup.com/p/510934/ will be held in Beijing  on November 14-15, and will attract more than 500 industry‌σ÷ε experts from domestic and foreign pharmaceuticΩ§♠☆al companies, biotechnology comp ÷§£anies, governments, associations, ε✔'law firms, intellectual property agents and oth&↕er companies to attend.

Official registration and consultati→Ωγ≠on channels:

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From :businessinsuranceU.S. commercial pro₩Ω₩€perty/casualty rates rose 5% on average in₹★ the fourth quarter of 2019, up from 4% in β™​>the third quarter, reflect↔¥★‍ing insurers’ intent to continue ‍>to increase prices across most l‍" ines, online insurance exchange≠&₩  MarketScout Corp. said Monday.α ​✔“Auto rate increases have been up all yea☆‍r long; however D&O (dire'β​♣ctors & officers) and professional rate incre≠‍§∑ases have spiked significantly®β$↕ in the fourth quarter,” Richard ®✔Ω Kerr, CEO of MarketScout Corp. said in a st♥®↓₩atement.Insurers are carefully analyzing £δtheir property exposure ¥♣s using catastrophe modeling tooλ≤®"ls, he said. “We expect many of the major prλ®∞operty catastrophe insurers to curtaβ♥il their 2020 writing© s in California brush and East and Gulf Coast ♦✔wind areas. Naturally∑♦, this will result in highλ÷≈er rates to insureds,” Mr. Kerr said.D&O liab♥•×∏ility rates increased by 8.25%, while comm&≠•&ercial auto increased ↔±₩β8% in the quarter, and professional liability r♦÷↔ates were up 6%, and umbrella/exγ±≥"cess rates were up 5.5%, according to &↓>∏MarketScout.Commercial properλ∏←€ty rates increased 5.25% in the λσ✔♣quarter, and business inte∞π✘Ωrruption rates were up 5%, while all other lin≤>∞es showed smaller increases§ γ₩, except for workers compensation, whe¥"re rates fell 1%, MarketScou↕←™t said.By industry class, tra∑∏nsportation and habitational saw the highest a<ε verage rate increases at 9% and 8.25% rπ&§espectively, MarketScout said.Large accoun'​ ts – those with $250,001 to $1 mill×®↕÷ion in premium – saw a ra≥✘♣te hike of 5.5% in the fourth quarte δ≥↓r, as did jumbo accounts, which have more than $¶♠ ♠1 million in premium. Small accounts – those wit ←←h up to $25,000 in pr≥ ©emium – were up 5%, while medium a‍✘ccounts – those with $25®↕♣≈,001 to $250,000 in premium – were up 4.5%.The©↑ “steady trend” of upward rates refle←©cts insurers’ plans to continue incr© easing prices across all lin≈≤÷✔es except for workers compensation, M♠¥δarketScout said.Organizer:China I§≠↑nsurance Digital & AI Developmeπ≠nt 2020Web:http://en.zenseegroup.com/p/560573/Con"α≈←tact:Ann 021-6565030±≈♥5

From :insurancejournalIt was a relativ ®€ely quiet year for the Southeast in ≈→ terms of major catastrophes compa♣∏≠€red with 2018 when Hurricane’s Michael∞Ω and Florence caused major damage in the reΩΩgion. This year, Hurri×₹cane Dorian sideswiped the Southeast coa§¥™st and made landfall o↔∞£↔n the Outer Banks of Nort ✔¥h Carolina but most of the area was ÷★≠spared. Still, Aon said economic dam♦ ≈age in the U.S. and Canada was p∞₩Ωoised to approach a comb§πined $1.5 billion.Florid©↓a spent the year recovering from Hurricanπε ∏e Michael, which was upgr←§aded to a Category 5 storm by NOAA ↔γin April. Florida officials have re♥®¶™peatedly called on the insurance ‍™¶industry to speed up the recovery p"₹₩rocess, with nearly 12% of claims still o×☆pen a year after the storm hit.Organizer:C↕♠hina Insurance Digital ✔¶♦& AI Development 2020Web:http:® //en.zenseegroup.com/p/560573/Co σ>ntact:Ann 021-65650305

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France-based eyewear maker Essilor Intβ₩©↔ernational S.A. has discovered fraudulent act®​&ivities at one of its factories in Thaσ₩​iland that could cause €190 million ($213 m∑ε₩∑illion) in financial losses t£ o the company, The Irish Times↕♦☆ reported citing Reuters. The company hεδ₹βas filed complaints in Thailand and ♣↓♣has fired all the involved e•£♥mployees. It hopes to reco↑∏ver the losses from froze€✔n bank accounts, insu↓<★rance and lawsuits.Organizer:Ω™China Insurance Digital &γα" AI Development 2020 ₹←Web:http://en.zenseegro​φ★up.com/p/560573/Contact:Ann 021-65650305

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