TUESDAY, OCTOBER 29, 2019
Gilead Sciences Inc. and Glympse®↕✘§ Bio, Inc., today annoα≥unced that the companies have entered intoε a strategic collaboration in♣↕ nonalcoholic steatoh≠♦λ↓epatitis (NASH) clini¥→cal development. Glympse Bio÷✔$’s proprietary synthetic biomarkers – bio↕♣engineered to identify stage and progression o✔•≥f disease as well as φ÷early detection of treatment respons€ €e – will be used to determine clinical trial pa♣₽"÷rticipants’ stage of disease at initiaλ÷δ☆l screening and to deφ÷≈©termine responses to study treatmeπ≥nt in Gilead’s NASH clinical program.
“We are excited about the oppδ∞ ortunity to partner with Glympse Bio to h'♣≤§elp inform our NASH development program,” said M¥ani Subramanian, MD, PhD €•Senior Vice President, Liver Diseases, Gil₽→♥ead Sciences. “By utilizin&"×Ωg this innovative technolog£"↓y, we hope to better characterize this complex d★₩isease and improve our understanding of how our c₹πompounds impact disease progress♠≤® ion.”
Glympse Bio’s proprietary t→π≈✘echnology, Glympse Inside™, combines syntheti€ αβc biomarkers with machine learning app→roaches to identify the stage and mon↕€itor progression of important, complex disease☆•s such as cancer, fibrosis, inflammation,→ and infections, in re÷★al time.
“We are very excited about partnerin∞★∑g with Gilead, a leader in drug deve®≥∏•lopment, to help drive earlieε↕r and more favorable ou¥ tcomes for patients,” said Carol>♠ε×ine J Loew, President ↑αand CEO, Glympse Bio.λ✘'≈ “Gilead’s commitment to developing innov<β☆ ative medicines in areas of hiγ✔× gh unmet medical need aligns with our mission oε♠f transforming disease det♣≤↔ection and measuring treatment response, al≈'≈l with the goal of helping improve≥₽≤₩ the lives of patients.”
information source:pharma focus Asia
The original link:https:https:https:/≤≈/www.pharmafocusasia.com/news/gilead-an <∑→d-glympse-bio-announce-str∞☆®ategic-collaboration-for-use-of-biom☆∑arker-technology-in-nash-clinical-developmen ≥↑±t
2019 Asia-pacific pharma IP Leader €£Summit:http://en.zenseegroup.com/p/510934/ will be held in Beijing on November 14-15, and will attract more than 500 industryσ÷ε experts from domestic and foreign pharmaceuticΩ§♠☆al companies, biotechnology comp ÷§£anies, governments, associations, ε✔'law firms, intellectual property agents and oth&↕er companies to attend.
Official registration and consultati→Ωγ≠on channels:
Contact:Ann
Phone: 021-65650305
From :businessinsuranceU.S. commercial pro₩Ω₩€perty/casualty rates rose 5% on average in₹★ the fourth quarter of 2019, up from 4% in β™>the third quarter, reflect↔¥★ing insurers’ intent to continue >to increase prices across most l" ines, online insurance exchange≠&₩ MarketScout Corp. said Monday.α ✔“Auto rate increases have been up all yea☆r long; however D&O (dire'β♣ctors & officers) and professional rate incre≠§∑ases have spiked significantly®β$↕ in the fourth quarter,” Richard ®✔Ω Kerr, CEO of MarketScout Corp. said in a st♥®↓₩atement.Insurers are carefully analyzing £δtheir property exposure ¥♣s using catastrophe modeling tooλ≤®"ls, he said. “We expect many of the major prλ®∞operty catastrophe insurers to curtaβ♥il their 2020 writing© s in California brush and East and Gulf Coast ♦✔wind areas. Naturally∑♦, this will result in highλ÷≈er rates to insureds,” Mr. Kerr said.D&O liab♥•×∏ility rates increased by 8.25%, while comm&≠•&ercial auto increased ↔±₩β8% in the quarter, and professional liability r♦÷↔ates were up 6%, and umbrella/exγ±≥"cess rates were up 5.5%, according to &↓>∏MarketScout.Commercial properλ∏←€ty rates increased 5.25% in the λσ✔♣quarter, and business inte∞π✘Ωrruption rates were up 5%, while all other lin≤>∞es showed smaller increases§ γ₩, except for workers compensation, whe¥"re rates fell 1%, MarketScou↕←™t said.By industry class, tra∑∏nsportation and habitational saw the highest a<ε verage rate increases at 9% and 8.25% rπ&§espectively, MarketScout said.Large accoun' ts – those with $250,001 to $1 mill×®↕÷ion in premium – saw a ra≥✘♣te hike of 5.5% in the fourth quarte δ≥↓r, as did jumbo accounts, which have more than $¶♠ ♠1 million in premium. Small accounts – those wit ←←h up to $25,000 in pr≥ ©emium – were up 5%, while medium a✘ccounts – those with $25®↕♣≈,001 to $250,000 in premium – were up 4.5%.The©↑ “steady trend” of upward rates refle←©cts insurers’ plans to continue incr© easing prices across all lin≈≤÷✔es except for workers compensation, M♠¥δarketScout said.Organizer:China I§≠↑nsurance Digital & AI Developmeπ≠nt 2020Web:http://en.zenseegroup.com/p/560573/Con"α≈←tact:Ann 021-6565030±≈♥5
From :insurancejournalIt was a relativ ®€ely quiet year for the Southeast in ≈→ terms of major catastrophes compa♣∏≠€red with 2018 when Hurricane’s Michael∞Ω and Florence caused major damage in the reΩΩgion. This year, Hurri×₹cane Dorian sideswiped the Southeast coa§¥™st and made landfall o↔∞£↔n the Outer Banks of Nort ✔¥h Carolina but most of the area was ÷★≠spared. Still, Aon said economic dam♦ ≈age in the U.S. and Canada was p∞₩Ωoised to approach a comb§πined $1.5 billion.Florid©↓a spent the year recovering from Hurricanπε ∏e Michael, which was upgr←§aded to a Category 5 storm by NOAA ↔γin April. Florida officials have re♥®¶™peatedly called on the insurance ™¶industry to speed up the recovery p"₹₩rocess, with nearly 12% of claims still o×☆pen a year after the storm hit.Organizer:C↕♠hina Insurance Digital ✔¶♦& AI Development 2020Web:http:® //en.zenseegroup.com/p/560573/Co σ>ntact:Ann 021-65650305
From:businessinsuranceeinsurance renew'♠ als at Jan. 1, 2020, mainly saw φγsingle-digit increases, with some exceptions, acc <ording to reports by reinsurance brokers released ÷↔σ Thursday.Willis Re, th$®e reinsurance brokerage of Willis ∑↕Towers Watson PLC, and Guy C★ασarpenter & Co. L₹$LC, a unit of Marsh & McLennan Coπ"s. Inc. both reported that year-end reinsu÷±rance renewals varied by accπ"ount and region, but the ∞₹∏∏retrocessional reinsurance was under♣σπ pressure.Rates on line for property c&£σatastrophe reinsurance programs reα→mained stable and property per ri Ωδ£sk pricing was driven by individual program↔ ©ε performance, the Willis report said.Aγ£lthough some Lloyd’s of London±ε syndicates took firm positions on rate increaseδ₽ s and the London market author★↑•λized capacity decreased, that capactiy was r±δeplaced by new capita≤σl and a strong supply from∏→β other markets, Willis Re said.U.S. loss-free☆→ accounts renewed at flat to up 10 λ☆↔% while those with losσ↔₽↑ses saw increases of 10% to 50%, the Willis Re≈₽ report said, which was amo ¥↕ng the largest increa₽ &£ses. Property catastroα¥phe accounts without losses¶ ∞ renewed at flat to uε↔p 5%, while loss hit acφ₽∏counts were up 10% to 20%, Willis Re said.Accoε ×rding to the Guy Carpente∏♠₽©r report, the brokerage’s global property ca☆$♦tastrophe rate on line index rose 5% in 201€•9.According to the Willis Re report, other l"✔arge increases were seen i±↔∞n Central and Eastern Europe, where &→§&property programs with losses ¶¥ saw increases of 5% to 20%, a§β÷nd Canada, where such accounts re€£≤ newed up 10% to 40%.Most other regions and $≤countries saw property increaα÷ses in the single or low double digits, the repΩ®σort said.The Jan. 1 renewals saw some “difficult$↕✔✔” negotiations, accordin∏®g to a letter in the rep ♥& ort from James Kent, globεΩ✘al CEO, Willis Re.The Guy Carpenter repo∏&÷✔rt said the reinsurance marke✘<✘≤t was “asymmetrical,” adding “this♥× is certainly not a one-size-fits-a₽•♣ll market” and while•≈≠ overall capacity remained adequat¶↔↑"e, “allocated capacity→✘Ω tightened notably in stressed classes.”D ¥₽©edicated reinsurance capitalδφ rose 2% in 2019 and↕™¥↔ the year saw approximately $60 billion in globa₩₽≈♦l insured catastrophe losses, aλ ₩ccording to Guy Carpenter, which was signifi∑≤'cantly lower than 2017 an↑≠☆d 2018.Alternative capital, however, c$✘ontracted by approximately 7% percent “as✔₩♥ investors were more cautious with₽♣♠≈ new investments after assessing market dynamβ∞σics and pricing adequacy,” Guy Carpe↕×nter said.The retrocession market “was chal$♠lenged … by trapped capital, a lack o≠✔f new capital and continued redemptions fr''om third-party capital providers,” γa statement issued with the Guy Carp ★®enter report said.Ho∏∏$wever, significant retrocess☆®"±ion providers returned to the market i≈≥¥n the past two weeks, Willis Re said.Organizer:C♠&Ω↕hina Insurance Digital & AI Develop₽€§×ment 2020Web:http://en.zenseegroup.com/p/560•☆573/Contact:Ann 021-65650305
Major information technology compani↑↓×es in India are runninβ₹→∏g the risk of termination of €♥γtheir $1 billion contrac§÷®φts following Boeing Co.’s decision to halt theΩ®β production of its 737 Max jets, MoneyControl re∏≤ ported citing the Business Standa"£ ♥rd. Companies like Tata Conβ±↓sultancy Services Ltd., Infosys Ltd.,✔'÷ HCL Technologies Ltd., Cyient Ltd. a $←©nd L&T Technology Services Ltd. have out₩¶←♣sourcing contracts with Boeing or its suppliers aγ>'™nd Boeing’s jet crisis is expecte←≥d to affect these IT compαγ↔•anies in the short run.From:♥<£businessinsuranceOrganizer:China Insura ∏¥nce Digital & AI D♥>evelopment 2020Web:http://en.ze×♣nseegroup.com/p/560573/Contact:Ann 021-6≤≠₽5650305
France-based eyewear maker Essilor Intβ₩©↔ernational S.A. has discovered fraudulent act®&ivities at one of its factories in Thaσ₩iland that could cause €190 million ($213 m∑ε₩∑illion) in financial losses t£ o the company, The Irish Times↕♦☆ reported citing Reuters. The company hεδ₹βas filed complaints in Thailand and ♣↓♣has fired all the involved e•£♥mployees. It hopes to reco↑∏ver the losses from froze€✔n bank accounts, insu↓<★rance and lawsuits.Organizer:Ω™China Insurance Digital &γα" AI Development 2020 ₹←Web:http://en.zenseegroφ★up.com/p/560573/Contact:Ann 021-65650305