THURSDAY, OCTOBER 17, 2019
HitGen Inc. today announced that>→© it has entered into a drug d ↕αφiscovery research collaborγ♠ε™ation with Galapagos NV t$Ωβ•o identify potential small molecule lea÷↓↑ds against targets o'<f interest to Galapagos NV. In>₽>₩ this collaboration, HitGen×φ£ will apply its technology ≤₽♣platform, based on DNA-encoded library γφ₩$design, synthesis and interrogation, ₹&→to discover novel leads. Under the term ×s of the agreement, HitGen will receiveΩ✘↕≥ an undisclosed upfront payment and will b♠≠✔&e eligible for milestone paymen'©"αts from Galapagos NV.
“We are delighted to enter →> this collaboration with Ga•↔₹lapagos NV, a leading biotechnology co →★→mpany, specializing in the discovery and d≥™evelopment of small mo✘☆±∞lecule medicines with novel m☆odes of action. We believe the colla&♠₩boration reinforces the ro↑¥¥'le of HitGen’s platform in theε↕ rapidly developing field of DN$±A-encoded chemistry. We will work cφ™≤losely with Galapagos NV scien←α<✔tists to generate new small-mo"δ★lecule lead compounds for their resear ∞Ω★ch programs to help bring transformative medici&↑∑¶nes to patients,” said Dr. Jin Li, Chairma✔<n of the Board and Chief Executive Officer of Hit>≤×Gen.
“We look forward to working with≤ HitGen and tap into their established DEL tech≠αnology platform to complement our internal scr<εeening and drug discovery technologies.” s"δ∏aid Romain Gosmini, Director Medicinal"®✔ Chemistry at Galapagos.
information source:pharma focus Asia
The original link:https:https://wwwΩ£.pharmafocusasia.com/news/hitgen-enters-into-dna- ÷encoded-library-based-drug-discovery-resea•<↑rch-collaboration-with-galapagos-nv
2019 Asia-pacific pharma IP Leader Su$δmmit: http://en.zenseegroup.co₽₩♣ m/p/510934/ will be held in Beijing on November 14-15, and will attract more than 500 ind♦₹ustry experts from domestic and↑¥ foreign pharmaceutical companies, biotechnologλ$y companies, governm✘β♠↑ents, associations, law firms, intellectual proπ®≈₩perty agents and other companies to attend.
Official registration a✘™"∏nd consultation channels:
Contact:Ann
Phone: 021-65650305
From :businessinsuranceU.S. commercial pro£σ±¥perty/casualty rates rose 5% on averσage in the fourth quarter of 2019, up fro≈®¶m 4% in the third quarter, r€≥®eflecting insurers’ intent to continue to increδΩ¥ase prices across most lines, online insura¥εnce exchange MarketScout Coγ÷ ®rp. said Monday.“Auto rate i δncreases have been up all year αεσ©long; however D&O (directors &★₩★✔ officers) and professional rate★&™ increases have spiked significantl↓$ y in the fourth quarter,” Rich€♦©ard Kerr, CEO of MarketScout ✘•Corp. said in a statement.Insu¶₹ rers are carefully analyzing their property eδβπ™xposures using catastrophe modeling tools, he sa₹≥♣∑id. “We expect many of th>∏γ©e major property catas£ ≠trophe insurers to curt↔✘≤ail their 2020 writings in California brusφ↑≥h and East and Gulf Coast wind areas. Natura$δlly, this will result in higher rates to i•≈ nsureds,” Mr. Kerr said.D&O liability r≥™ates increased by 8.2∏→÷©5%, while commercial auto increased 8% in the↑×↓ quarter, and professio±®nal liability rates were up 6%, and umbrella/e$<₹↕xcess rates were up 5.5%, according to Ma♦ ✘ rketScout.Commercial property rates increasedα" 5.25% in the quarteφ↔¶r, and business interruption rates were up 5%,∞↕♣ while all other lines showed smaller i©∑γ♠ncreases, except for workers compensation, wh$©βere rates fell 1%, MarketScout said£™δ↑.By industry class, transpo←♦rtation and habitational saw the highe←•∏₩st average rate increases at 9% and 8.25% ♥€ε¥respectively, MarketScout said.Lφγarge accounts – those with $250,♠₽≠001 to $1 million in premium – saw a rat¥≈λe hike of 5.5% in the fourth quart₽™er, as did jumbo accounts, whi♥<ch have more than $1 mi₹§≥llion in premium. Smal€δ♠l accounts – those with €&up to $25,000 in premium – ≤♠ were up 5%, while mediu↕λm accounts – those with $25,001 to $250,000 in ≥βpremium – were up 4.5%.The×& “steady trend” of upward rates reflects >£insurers’ plans to continue incr>£easing prices across all lines except for wor¥÷¶kers compensation, MarketSc"₩'out said.Organizer:China Insurance Digital &am'♦ p; AI Development 2020Web:http://en.zens↑φ✘eegroup.com/p/560573/Contact:Ann 021-6≈✔✘5650305
From :insurancejournalIt was a relatiΩ€vely quiet year for the Southe♦™↓πast in terms of major catastro♥☆βphes compared with 2&ε≠018 when Hurricane’s Mic$✘≠∑hael and Florence caused major damage in the ↓✘<region. This year, Hu♦≈rricane Dorian sideswiped the Southeast c£<✔oast and made landfall on the Outer Bank♣γ§≠s of North Carolina but most of the area was spΩδσared. Still, Aon said eco₹$nomic damage in the U.S. and Canada was ♥Ωε★poised to approach a combined εε™$1.5 billion.Florida spent the ±&↑♥year recovering from Hurricane Michael, which&nbs↑₩λ∑p;was upgraded to a Category 5 storm by NO↓÷π✘AA in April. Florida §↑↕↔officials have repeatedly called on t≤ ♥he insurance industry to speed up t•♥he recovery process,☆♣ with nearly 12% of claims still open a year Ω£after the storm hit.Organ☆"₩ izer:China Insurance Digital & AI Develop×≤ment 2020Web:http://en.zenseegroup.co®♦γm/p/560573/Contact:Ann 021-65650305
From:businessinsurancee←←insurance renewals at Jan. 1, 2020, mainlγ≈♥λy saw single-digit increa♠✘ses, with some exceptions, according to re¥•↔ports by reinsurance bro♦↕÷kers released Thursday.Willis Re, the reinsur£→ance brokerage of Willis ✔₽↑Towers Watson PLC, and Guy Cπ÷λarpenter & Co. LLC, a unit of M₹♠∞πarsh & McLennan Cos. Inc. both >Ω≥§reported that year-end reinsurance renewals varε←ied by account and region, but ±™the retrocessional reinsurance was under p≤®$₩ressure.Rates on line for property catastrophe ↔↔♣reinsurance programs rem↔αδained stable and property per risk pr✔♠"icing was driven by individual program performanc'>↓e, the Willis report said.Although some Lloy>✘÷d’s of London syndicates took "σfirm positions on rate increases →¶and the London market authorized capacity decre§₹∏∑ased, that capactiy was replaced by new capital a₹'φnd a strong supply from other markets, Will∞•↕αis Re said.U.S. lossδ-free accounts renewed→λ at flat to up 10% while those with losses sσ≠Ωaw increases of 10% to 50%,♥♥ the Willis Re report said←♠≈>, which was among the larges∑ ©t increases. Property catastrophe accounts§£®± without losses renewed at ₩σ∏flat to up 5%, while loss hit accouε♥•nts were up 10% to 20%, Willis Re said.Accordiσ¥σng to the Guy Carpenter report, t♥ε©he brokerage’s global ≠↑property catastrophe rate on line ind↕"λex rose 5% in 2019.According to the Willγσis Re report, other large i✔§→ncreases were seen in Central a¶≥nd Eastern Europe, where property programs wit★γΩh losses saw increases of 5% • to 20%, and Canada, where such accou£βnts renewed up 10% to 40 &®★%.Most other regions and countries saw pr≈εoperty increases in the single or low double© digits, the report said.The Jan. 1 ¥₹©renewals saw some “difficult” negotiations, acc€©γΩording to a letter in the report froδ∞≈m James Kent, global CEO, Willis Re×≥≠♣.The Guy Carpenter report said the reinsurance m©÷arket was “asymmetrical,” addi→©βng “this is certainly not a one-size-fits-δπall market” and while overall capacity remain☆×ed adequate, “allocated capacity tighteneσ÷§∞d notably in stressed classes.”Dedi↑♦ 'cated reinsurance capital rose 2% inβ→≠ 2019 and the year saw approximately $60 ♦×billion in global insured catastrophe l≠↑™λosses, according to Guy Carpeγ↔nter, which was significantly&π↔™ lower than 2017 and 2018.Alternatγ∏≈ive capital, however, contracted by appro£&•ximately 7% percent “as i™€®nvestors were more cau&'Ω€tious with new investments after assessing mδ arket dynamics and pricing adequacy,” Guy Carpen€☆∞ter said.The retrocession market “was chal≠♦lenged … by trapped capital₩♠♣, a lack of new capital and continue→♠d redemptions from third-party capita✔₩∞ l providers,” a statement issued with the Guyγσ Carpenter report said.However, significant×♥₩ retrocession providers returned to "×γ↑the market in the past two weeks,↑¥ Willis Re said.Organizer:China Insurance Digi≥"™tal & AI Development 2©¶020Web:http://en.zenseegrou≈λp.com/p/560573/Contact:Ann 021-65650305
Major information technology companies in In&₩§dia are running the risk of termin✘$¶ation of their $1 billion contracts fo>↔llowing Boeing Co.’s decision to h♠→≥alt the production of its 737 Max je£σ§ts, MoneyControl reported citing γthe Business Standard. Compan₽©ies like Tata Consultancy Services Ltd., Infosys'€ Ltd., HCL Technologies Ltd., Cyien♥λ∑t Ltd. and L&T Technology♦→Ω× Services Ltd. have out'∏sourcing contracts with Boeing o™✔×∏r its suppliers and Boeing’s jet crisis is expΩ ☆∏ected to affect these IT c≥<←ompanies in the short run↑γ&.From:businessinsuranceσ≥←Organizer:China Insurance Digital & AI De≥ velopment 2020Web:http://en.zenseeg₽σroup.com/p/560573/Contacδ↓γt:Ann 021-65650305
France-based eyewear maker Es♠™εΩsilor International S.A. has discovered fr$&>audulent activities at one of iαγ™ts factories in Thailand that cou♥₽•∞ld cause €190 million ($213 million££) in financial losse×>₩s to the company, The Irish Times report♣ ed citing Reuters. The company ha₹δ♦$s filed complaints in Thailand a≥ nd has fired all the involved e≤♣®∑mployees. It hopes to recover the l'ε osses from frozen bank accounts, insurance ₩Ω ✘and lawsuits.Organizer:China£★₹ Insurance Digital & AI Develop↓ε≠ment 2020Web:http://en.zen✔™±seegroup.com/p/560573/Contact:Ann 021-6♥§5650305