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La Jolla Pharmaceutical Company Receives European£→ Commission Approval for GIAPREZA™ (angiotensin I  ♥÷I)
2019-09-03

La Jolla Pharmaceutical Compan'€♥✘y, a leader in the discover✔​&y, development and commerci₽✘$alization of innovative therapies intended to£‌↔ significantly improve∑∞ outcomes in patients suffering from life-threatλ<♠<ening diseases, today announced that th‍↔σe European Commissio∞¶n (EC) has approved GIAP©"¥REZA™ (angiotensin II) for the∑$✘ treatment of refractor✔★y hypotension in adults with sepλ≤tic or other distributive shock who remain ♣×hypotensive despite adequate  ¥Ω volume restitution and application of cate‍αcholamines and other available vasopressor th§™erapies.

“We are pleased with the European Commission’s a ×pproval of GIAPREZA and look fo§π♣rward to bringing this new treatment option✔₹> to the many critically ill Europea∞ ↕n patients suffering from σ♦septic or other distributive shock,π​” said George F. Tidmarsh, M.D., Ph.D. ↔ε, President and Chief Executφ‌ive Officer of La Jolla. “We are appr←♥¶eciative of the patient∑£s, families and dedicated cri&δ¥tical care teams who made th×★e development of GIAPREZA possible.”

The EC’s approval is ba↕§sed on data from the ATHOS-3 (Angiot∞₩ensin II for the Treatment of High-Output α∏Shock) Phase 3 study, ε which established the safety and efficacy of GIAβ"<PREZA in adults with septic or other§♦₽ distributive shock. The EC"☆↔€’s decision is applicable to thα©★e 28 European Union member countδ→ries. Approval will also be recognized in ×↓γIceland, Norway and Liechtens≥∏$₩tein.

the 2019 Asia-pacific pharma IP Leader Summit: λ∞§http://en.zenseegroup.co↕€π×m/p/404716/ will be held in Beijing  on November 14-15, and will attract more than 500 industry exp∑♣×erts from domestic and forei♥≠gn pharmaceutical companies×$, biotechnology companies, governm​←≥ents, associations, law firms, intellectu$£al property agents and otherλ☆₽β companies to attend.

Official registration and coε‌₽nsultation channels:

ContactAnn

Phone: 021-65650305

EmailMarketing@zenseegroup."≥₹φcom

http://en.zenseegroup.com↔φ₹σ/p/510934/

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From :businessinsuranceU.S. commercial pro≠'€perty/casualty rates rose 5% on average in ≤↑λ$the fourth quarter of 2019Ω☆♥$, up from 4% in the third quarter, reflecti↕σng insurers’ intent to continue$∞ to increase prices across most  ​lines, online insurance exchange Mark↕₽ etScout Corp. said Mon"≈ <day.“Auto rate increases have been u‌™​p all year long; however D&O (directors &‌↔✘ officers) and professional r↑•£ate increases have spiked sign¶≤ificantly in the fourth quarter,” Richard Kerr,↕ > CEO of MarketScout Corp. said inπβδ a statement.Insurersσ←§™ are carefully analyzing their pro©"perty exposures using catastrophe mo♦∏₹‍deling tools, he said. “We expect many of the  φmajor property catastrophe insurers to cur✘♥‍≥tail their 2020 writings in California brush a αnd East and Gulf Coast wind areas. Natπ≥urally, this will result in higher rat≈Ω≠"es to insureds,” Mr. Kerr said.D&O liabili'®ty rates increased by 8.25%, while commercial au≈®to increased 8% in the quarter, and profession≥∏∑✘al liability rates w>φ$ere up 6%, and umbrella/excess rates w£Ωere up 5.5%, according to Marke£'×tScout.Commercial property rates increased 5.25% ε>∞in the quarter, and busin≤↑ε<ess interruption rates wereδ  up 5%, while all other lines show>→ed smaller increases, except for workers compen ☆↔sation, where rates fell 1%, MarketSλ≤₹↔cout said.By industry class, transportat♠"™ion and habitational saw the highe≠<₹♠st average rate increases at 9% an​π"∏d 8.25% respectively, MarketScout s₹ aid.Large accounts – those with¶☆γ≠ $250,001 to $1 million↕₩± in premium – saw a rate©±$♥ hike of 5.5% in the fourth quarter, a÷↔& s did jumbo accounts, which have more than $1 mil≥↔lion in premium. Small accounts – those with ‌‍₹up to $25,000 in premium – were up 5%, while medi‍φλum accounts – those with♦✘♥ $25,001 to $250,000 in premiu≈¥δ¶m – were up 4.5%.The “steady tr→✔₹☆end” of upward rates reflects insure≤¶✔rs’ plans to continue incr​<₩®easing prices across ≥σall lines except for workers compensatφ δion, MarketScout said.Organizer:China↓ ≠↕ Insurance Digital & AI Development 202≠γ↕0Web:http://en.zenseegroup.com/p'✔/560573/Contact:Ann 021-65650305

From :insurancejournalIt was a relatively quiet ✘÷  year for the Southeast in term ε↑→s of major catastrophes compaγ‍↕•red with 2018 when Hurricane’s Miε‍chael and Florence caused major damage in>'↓☆ the region. This year, ∏>∑♣;Hurricane Dorian sideswiped the Southeast€<≠≥ coast and made land∞★ε₹fall on the Outer Banks of North Carolina §>♠'but most of the area was spared. Still,&nbΩ↔  sp;Aon said economic damage in t∏₽he U.S. and Canada was poised ← to approach a combin§<♠ed $1.5 billion.Florida spent the year ★®"γrecovering from Hurricane Michael, which&nbs↓€↔εp;was upgraded to a Categor≈‌↓©y 5 storm by NOAA in A™←£pril. Florida officials have repeatedly cal ​α¶led on the insurance industryΩ®® to speed up the recovery prφπλocess, with nearly 12% of claims still open a y‍δπear after the storm hit.Organizer:China Insuran ‌↕ce Digital & AI Developme‍'∑nt 2020Web:http://en.zenseegroup.com/p/56057€♣3/Contact:Ann 021-65650305

From:businessinsuranceeinsurance renewals at™β™ Jan. 1, 2020, mainly saw single-$§>Ωdigit increases, with some exceptions, accord>™♥ing to reports by reinsurance brokers released ThΩ☆ursday.Willis Re, the ∞‌ >reinsurance brokerage of Willis Towers Watson ♣÷$PLC, and Guy Carpenter & Co. LLφ®♥C, a unit of Marsh &∑✔∞; McLennan Cos. Inc. both reported that year-end ≤♣ εreinsurance renewals varied by account and regiΩ≈on, but the retrocessi₽✘<®onal reinsurance was under pressure.Rates on©∞₩ line for property catastropheγ$₽γ reinsurance programs remained stable and propeΩ₩rty per risk pricing was driven b₹®Ω>y individual program performan​♥ce, the Willis report said.♥ Although some Lloyd’s of London syndic♠'ates took firm positions on rate increases an'÷d the London market authorize←​d capacity decreased, that capactiy was repλ>♦laced by new capital ©↑and a strong supply from other markets, Willis ε•Re said.U.S. loss-fre≠σ∑e accounts renewed at flα≈at to up 10% while those with losses sawλφ‌ increases of 10% to 50%, the Willis♦↕ Re report said, which was∏​α among the largest increas♦ es. Property catastrop∏β♥•he accounts without losses renewed at flat to uπ←↓γp 5%, while loss hit∞​♣ accounts were up 10% to 20%, W§δillis Re said.According to the Gu↓ σ​y Carpenter report, the brokerage’s gλ‍∏∑lobal property catastrophe rate on line index rσ★ose 5% in 2019.According to the Willis Re report,←♠≈ other large increases were seen in Centra€♠ ¶l and Eastern Europeδφ♥Ω, where property programs with lo©♠≠sses saw increases of 5%$&&€ to 20%, and Canada, '™where such accounts renewed up 10% to 40%♥♣↓.Most other regions and co↕"untries saw property increase→©s in the single or low double digits>±→β, the report said.The Jan. 1 renewβ♥≠als saw some “difficult” neg→≠δ₩otiations, according to a le™>‌↑tter in the report from James Kent, global$↓ ♠ CEO, Willis Re.The G ∞πuy Carpenter report said the reinsurance m♣✘arket was “asymmetrical,” adding →∑&“this is certainly not a one-si↕♠∏ze-fits-all market” and while overall capac↔>≥≈ity remained adequate,¶‍ “allocated capacity tightened notab"​ly in stressed classes.”Dedicated rein¥‍β★surance capital rose 2% in 2019 and the year λ≤saw approximately $60 billion in global insu≤÷red catastrophe losses, acco​ rding to Guy Carpenter, which w±&as significantly lower than 201↔"γ7 and 2018.Alternative capital, ho↕€wever, contracted by app¥☆$roximately 7% percent♣> “as investors were more cautious with ne§§ w investments after assess←♥★<ing market dynamics and pricin♦φ→$g adequacy,” Guy Carpenter said.The retroce↔¶£ssion market “was challeng•αed … by trapped capital, a lack of new capital ∞♥and continued redemptions  ¥from third-party capital provi✔ £÷ders,” a statement iss≥§ued with the Guy Carpenter report said. ₽≤$However, significant retrocession providers retur←‌ned to the market in the past two weeks, Willi‍>♥s Re said.Organizer:China Insuranceσ> Digital & AI Development 2020Web:http://en.z♥™∏↑enseegroup.com/p/560573/Contact:Ann 021-6565030©₽¶∏5

Major information technology compan ♥♠ies in India are running the risk÷♦↓φ of termination of their $1¶ ©≥ billion contracts following BoeiΩ↑ε→ng Co.’s decision to halt the produc✔×αφtion of its 737 Max jets, MoneyCont∏εrol reported citing t¶π&δhe Business Standard. Companies like®↓ Tata Consultancy Services Ω∑♦€Ltd., Infosys Ltd., HCL Technologies Ltd., Cyien←δt Ltd. and L&T Technology β>↕©Services Ltd. have out ↑×±sourcing contracts with Boeπ£©ing or its suppliers and Boeβ§↔ing’s jet crisis is expected to aff£→ect these IT companie×£s in the short run.From:businessinsuranceOrgani→φzer:China Insurance Digital &"™; AI Development 2020We↔∞♣≠b:http://en.zenseegroup.c↕£ε→om/p/560573/Contact:Ann 021ε✘→-65650305

France-based eyewear maker Essilor β σ₽International S.A. has$♥§ discovered fraudulent activities at o∏αne of its factories ≥♠↕≥in Thailand that could cause €190 million ($2 ×13 million) in financial losses to the coβφmpany, The Irish Times reported c"✘✘iting Reuters. The cδ♥ompany has filed com‌§plaints in Thailand and has f≈•ired all the involved employees. It hopes to ♥$recover the losses from frozen bank acco®£unts, insurance and lawsuitγ≠ε©s.Organizer:China InsuranεΩ≥ce Digital & AI De¶∑←‍velopment 2020Web:http://en.zenseegroup.com/p/56↔₹₹0573/Contact:Ann 021-65650305

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