Velabs Therapeutics GmbH, a biotech company fo↓∏✔₩cused on the rapid screening of functional ther'γεapeutic antibodies, today an¶↓↓₹nounces that it has entered into a ≠δ∑∑partnership agreement with Ω₩alytas therapeutics GmbH (alytas), to jointly d↔™♥✘evelop modulatory and functional antibodies for ©a novel immune-based therapy again£st obesity. The collaboration will le¶<verage Velabs' proprietar♦>&y microfluidic-based technology for rapid ∏$®functional antibody screening. V<&&elabs will be entitled to royalties from←π₩ the worldwide sales ∑£of products that result from the collaboration.≠™
Velabs Therapeutics is a₩♣ pioneer in microfluidi∞♠★↓c technology for the screening of antibodies ±¥with modulatory function on complex signa✔" ling proteins. Its proprietary®∞≠→ high-throughput screen₽↕®&ing platform makes it possi±αble to test millions of correctly¥× paired, fully naturalεδ∑♥ human and mouse IgGs for therapeutic eff∏≈φects. Results are achiδeved in only a fraction of the time required by ≠≈∞φother technologies. The Company off≥φers customized screening services for users world☆÷wide. In addition to the exeεΩσcution of service projects, €πVelabs is currently building its own pipeline o₽€φf therapeutic antibody ca♠>ndidates for further joint developmen€Ωt with pharmaceutical partners.
Alytas specializes in the research of fat m←∞∞ etabolism in connection with obesity, and has i✘λ♠dentified and validated targ" et genes for the development of§→> a novel immune-based obesity treatme§≈↔>nt. Its program is based on♠≈ε™ a number of proprietary protein♦> epitopes with high relevance for the imm'✔$unological regulation of excess adipocytes,₩∞© and has already been conc↑™&αeptually confirmed in vitro and in vivo.
Christoph Antz, Managing Direct↓®✘≈or of Velabs, said:
"We are pleased to h₩<πave reached this partnership agreement with a"• lytas, which will allow for the developme≥¶nt of a completely new®™♣ treatment option for£ obesity. The collaboration will benefit f→'"rom our expertise in rapid screφ'ening and the generati↓₹∏←on of functional antibodies on complex s¶∞×ignaling proteins. This knowled•↑©ge will be instrumental in developing a first♦ε mover immunotherapy for obesity andσ£< can help to significantly redu∞♦ce the global increase in associated co-mor✘≤bidities such as diabetes and car↑↕diovascular disease."
2019 Asia-pacific pharma IP Leader ≠✘↓Summit: http://en.zenseegroup.com/p/404716/ will be held in Beijing on November 14-15, and will attract more than 500 industry experts® from domestic and for§"eign pharmaceutical companies, × biotechnology companies, governments, associatε£ions, law firms, intellectual propeγ¥÷¶rty agents and other comp€"'anies to attend.
Official registration and consultat♣™ion channels:
Contact:Ann
Phone: 021-65650305
From :businessinsuranceU.S. commercial"γ÷ property/casualty rates rose ≥ 5% on average in the fourth qu< arter of 2019, up from 4% in the third quart¥↓er, reflecting insurer÷©≥₹s’ intent to continue to i₽₩♣ncrease prices across most lines, online αγσinsurance exchange MarketScout Cor↑εp. said Monday.“Auto₩ δ rate increases have been up all yea$&≥r long; however D&am♣λ'p;O (directors & officers) and ↕≤professional rate increases have spiked significa↕∏≈βntly in the fourth quarter,” Richard Kerr, CEO±β of MarketScout Corp. said iα✔"¶n a statement.Insurersεφ₽¶ are carefully analyzing their p↓β♦δroperty exposures using catastrophe modeling too♣×←™ls, he said. “We expect many of the major pr☆πoperty catastrophe insurers to curtail t↓≤heir 2020 writings in California brush and Eas£t and Gulf Coast wind areas. ★→♦↑Naturally, this will result i©π≥σn higher rates to insureds,” Mr. Kerr said.D&am㙥↕p;O liability rates increased by 8.25%, wh€∑"♥ile commercial auto increas•γed 8% in the quarter, and™← professional liability rates weΩ$re up 6%, and umbrella/excess rates were u®δp 5.5%, according to ∑®✔★MarketScout.Commercial prope• ≥rty rates increased 5.25% in the γ↕quarter, and business interruption rates were uβ×∏p 5%, while all other lines showed smal≥₩ler increases, except for £≈workers compensation±α∑≤, where rates fell 1%,™₩ MarketScout said.By industry claγ©∏ss, transportation and h↔∞abitational saw the highest average rate increa<✔≥®ses at 9% and 8.25% respectively, MarketScout¶✘ said.Large accounts – those with $2§ ®50,001 to $1 million in premium – saw a ra →≤te hike of 5.5% in the fourt•™♦h quarter, as did jumbo accounts,σ"£ which have more than $1 million in prem¥®☆∑ium. Small accounts – tho↓→ se with up to $25,000 in pβ↓remium – were up 5%, while mediuφ≠±m accounts – those with $25,001 to $250,000♠₩↓ in premium – were up 4.5%.The “steady t₩™₽<rend” of upward rates reflects✔Ωφ★ insurers’ plans to c∞∞ontinue increasing p♦>rices across all lines ex÷∏✔cept for workers compensation, Market↑∑ Scout said.Organizer× ✔ε:China Insurance Digital &←★; AI Development 2020Web:http:/✔σ/en.zenseegroup.com/p/560573/Contac≥☆✔t:Ann 021-65650305
From :insurancejournalIt was a relat₽♦ ively quiet year for the Soutσ♣←heast in terms of majoλ↕$₩r catastrophes compared with 2☆∑↓018 when Hurricane’s M"₽ichael and Florence caused major damage in€'πσ the region. This year, Hurricane DorΩεαian sideswiped the Southe•♥♦ast coast and made landfall on ש©the Outer Banks of North Carolina butε♣∑ most of the area was spared. Still,&nb÷ sp;Aon said economic damage in±≈ the U.S. and Canada was poised to apε$proach a combined $1☆← ×.5 billion.Florida spent the year $↓≥₹recovering from Hurricane Michael, whi↕αch was upgraded to a Category 5 storm<Ω by NOAA in April. Florida officials have repeate≠σdly called on the insura÷♦₩nce industry to speed up ¶the recovery process, wit€€≈←h nearly 12% of claims still o♠φγpen a year after the storm hit.Oπ≥ ™rganizer:China Insurance Digital & AI Devel>¥opment 2020Web:http://en.zenseegroup.c₩®om/p/560573/Contact:Ann 021-65650305
From:businessinsuranceeinsurance r≤≥δ enewals at Jan. 1, 2020, mainly saw singl∏↑♣e-digit increases, with some ex'✘♦ceptions, according to reports by reins"urance brokers releaπ∞sed Thursday.Willis Re, the reinsurance broker ε®>age of Willis Towers Watso↑≤ n PLC, and Guy Carpenter &am♦₽≥∞p; Co. LLC, a unit of Marsh & ÷€; McLennan Cos. Inc. both φφ¥✔reported that year-end reinsurance renewals variβα♥ed by account and region, but the retrocessio≠∏nal reinsurance was under pressureγ∏&.Rates on line for property catastrophe reinγ₩↕surance programs remaγ÷λ±ined stable and property per ←♦>risk pricing was driven by i✔☆ndividual program performance, the Willisλ≥★ report said.Although some Lloyd’s of Lo♣'π↑ndon syndicates took firm positions on ≤φ♦rate increases and the London mar&ket authorized capacity de♠creased, that capactiy was replaced by α≈∞new capital and a strong sΩ↓$upply from other mar ®λkets, Willis Re said.U.S. lossλ₹♥λ-free accounts renewed at flat to up 10'§>σ% while those with lo★≈εsses saw increases of 10% to 50%, the Willis →÷Re report said, whic₩✔±h was among the largest increases. Property™≈ catastrophe accounts witho¥£☆©ut losses renewed at flat to up ♥≈<5%, while loss hit accounts were u¥≈₹p 10% to 20%, Willis Re said.δσAccording to the Guy Carpen♣≠$£ter report, the brokerage’s global≤∞♦ property catastrophe rate on line inde∏★≠x rose 5% in 2019.According to the Williσ'§✔s Re report, other large increases were se♦₹©en in Central and Eastern Europe, where proper©≤ty programs with losses saw i≈σncreases of 5% to 20%, and Canada, where such∞← accounts renewed up ±≈10% to 40%.Most other regions a<± nd countries saw property increases in the sin∏♠γgle or low double digi ✔$♥ts, the report said.The Jan. 1 >×≠renewals saw some “difficult” n¥₽×egotiations, according to a letter in ™ <the report from James £ Kent, global CEO, Willis Re.Th↓←×e Guy Carpenter report said the reinsurance mark∑§et was “asymmetrical,” adding “this is♦γ∏ certainly not a one-size-'♥<fits-all market” and while overall capacity remai↔<ned adequate, “allocated capacity tightened♦÷ notably in stressed classes.”Dedicated r>±♥↑einsurance capital rose 2% in 2019 and the year γσ±saw approximately $60 billion in global insured c"♠ atastrophe losses, according to Guy Carpente↑★≥&r, which was significantly lower ÷ than 2017 and 2018.Alternative capital, ✔€÷however, contracted by approximateΩ®•ly 7% percent “as investors were more cλ♥÷autious with new investments after assessi♥≠♠ng market dynamics and p ♠↑ricing adequacy,” Guy α'♥Carpenter said.The retrocession market “waα★®s challenged … by trapped capital, a lack of new≥" capital and continued redemption©↑s from third-party capital™∞ providers,” a statement issued with¥≠δ the Guy Carpenter rep₽☆ort said.However, significant retrocessio∞✘←n providers returned ✘♠to the market in the p¥λast two weeks, Willis Re said.Organi₽÷'zer:China Insurance Digital &amγ£♥p; AI Development 2020Web:http≥β://en.zenseegroup.com/p/560573/Con®→↕αtact:Ann 021-6565030•≈∏5
Major information technology c&σσ ompanies in India are running γ"the risk of termination of th✘σ×₹eir $1 billion contracts following Boei§★✘ng Co.’s decision to halt the product¶₽<ion of its 737 Max jets, MoneyControl reported ♣←☆±citing the Business Standard. Companies→✔ like Tata Consultancy Services Ltd., Infosys "ε$φLtd., HCL Technologies Ltd., Cyiβ₽≤←ent Ltd. and L&T T¶↔λechnology Services Ltd. have out±≠↓εsourcing contracts with Boein$λ×g or its suppliers and Boeing’s ≥ jet crisis is expected to affect these IT coδ♠'mpanies in the short run.From:busi>§←nessinsuranceOrganizer:China Insu≈$λ₹rance Digital & AI Developmen↓ t 2020Web:http://en.zenseegrou₩ p.com/p/560573/Contac&"♥t:Ann 021-65650305
France-based eyewear maker Essilor Internati∏onal S.A. has discovered fraudulent activiti✘ εes at one of its factories in Thailand that ≥₩could cause €190 mil↑&lion ($213 million) in fi®≤✔nancial losses to the company,←♦ The Irish Times reported&π citing Reuters. The company has fi ∏ led complaints in Thailand and has fire₩≠✘d all the involved employees. It ho★pes to recover the losse↔♥ s from frozen bank accounts, insurance and σ©lawsuits.Organizer:China Insurance¥ Digital & AI Deve✘™lopment 2020Web:http://en.zenseegroup.c♥om/p/560573/Contact:Ann 021-65650305