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Harbour BioMed and PPD Form Strategi₽'αc Collaboration to Develop Innovative ♣±♥Therapeutics for Onco ε¶¶logy and Immunology
2019-08-29

Harbour BioMed (HBM), a global clinical-st←α↑↓age biopharmaceutical company, and Pharmac™₽✘eutical Product Development, LLC (PPD), a ≈§Ω✘leading global contract research organization​♥  (CRO), today announced a strategic collaborati✘✔α≠on to develop HBM’s in≈§novative therapeutics in the fields ofπ±♣ oncology and immunology.

The selection of PPD as a preferred CRO par♣"≤tner enables HBM, which has operatio • ns in the United Stat‍‌≠☆es, the European Union and China,<φσ to conduct global clinical studies on its​≠φ☆ internal research pipeline. HBM and PPD r ↕ecently completed an Australian ethics co""♠$mmittee (EC) submission for HBM4003, an anti-ca₹ ↓αncer immunotherapy to target solid¶&  tumors. The companies achieved the key•‌₩® milestone ahead of ×αschedule, on the path to Phase I tria↑π®♠ls in Australia and the United State& s.

HBM has been developing a robust pip≥π↓eline in oncology and immunology since "≠the company was established in late 2016. Itσβs portfolio includes f"₩€ive clinical-stage, in-licensed compounds a>≠nd a rapidly emerging set of therapeut<γics generated by its internal dδ☆®iscovery efforts, as wel♣®©↑l as co-discovery/development coll÷φ♣♥aborations with academic institutions and biop✔★harmaceutical companies.

“As a rapidly growing, medium-sized biot§& ¶ech company with global op♦ erations, we value the way PPD’s global cap ↑$∑abilities and biotech-friendly approach b&εoth complement and extend our team’s decades of e₽☆∏xpertise in running global tr'≈ials,” said Jingsong Wang, M.D., Ph.D., fo¶φunder, chairman and chief executive off✘ε©☆icer of HBM. “I’m pleased that our coll"©±αaborative partnership already has enabled us ↓ to achieve the important milest™Ωone of our first global ¥× ₽EC submission, and ahead of our aggressive sche™∞​¶dule. We look forward to entering the ∏εclinical trial phase of our deve→ £&lopment programs with PPD as we pursue our glob♦ al vision and ambition of delivering next-g♦₽en therapeutics to ful☆$↕fill patient needs around the world.”

HBM is leveraging the services of P∞↕<PD® Biotech, which combines the global c≤φ​apabilities of PPD wit↑× ↑h the hands-on approach, dedication ≠™Ω©and innovative mindset that drive↑π the success of biotech companies.

“Our enthusiasm for the opportunity to su↔ $pport the development of HBM’s  ♥ ♠innovative assets is equal₩₩₩γed by our shared commitm÷∞ent to helping accelerate>>σ the delivery of life-changing thera±♦pies to patients,” said Anshul Thak γral, executive vice president and global head ¶&of PPD Biotech. “We believe pairing an inn♣ ​ovative biotech mindset with ou↔πγr scalable global development serα✔→¥vices is a powerful combination♦↑  for our customers.”

from pharma focus aisa

the 2019 Asia-pacific Pharmaceutical IP Leader Sα★&♠ummit will be held in Beijing on November 14-15, and will attract more than 500 industr¥★'y experts from domestic and forei<σ←gn pharmaceutical companies, biotechnolog↓±y companies, governments, associations, law f¥'≥irms, intellectual property agents and other≤¥ companies to attend.

Official registration and c↕↔Ω onsultation channels:

ContactAnn

Phone: 021-65650305

EmailMarketing@zenseegroup.com

http://en.zenseegroup.com÷♦&©/p/510934/

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From :businessinsuranceU.S. commercial property↓σ/casualty rates rose 5% on average in thε∞e fourth quarter of 2019,≈←≤  up from 4% in the third quarter, reflecting¥ γ↑ insurers’ intent to continue to increase prices≤®σ÷ across most lines, onli ₹♣↓ne insurance exchange MarketScout Corp. sai™"®d Monday.“Auto rate increases have been up al✔δ✔l year long; however D&O (directors & o★☆$fficers) and professional λ rate increases have s÷₽'λpiked significantly in the fourth qu ♥arter,” Richard Kerrσ♠, CEO of MarketScout Corp. said in a statemen®®δ↑t.Insurers are carefully analyzingΩ✘"♠ their property exposur★¶es using catastrophe modeling tools, he said. “W♦←✔♣e expect many of the major pr"​∏Ωoperty catastrophe insureγ∞®±rs to curtail their 20 "20 writings in California bru‌​φsh and East and Gulf Coast wind areas™↓€. Naturally, this will &$result in higher rates to ins'✔ureds,” Mr. Kerr said.D&O liabi"≠lity rates increased ↑♠§by 8.25%, while commercial auto inc↕™σ♠reased 8% in the quarter, and professional liab₹‌←ility rates were up 6%,↓☆←  and umbrella/excess rates were up 5.5%, a★±ccording to MarketScout.Com£ ∑©mercial property rates increased 5.25% in the qua∞↔↑✘rter, and business interruption ‌♥ ‍rates were up 5%, while☆☆ all other lines showed smaller increases, exceδε÷pt for workers compensaπ✔≤>tion, where rates fell 1%, MarketScout sa♠€id.By industry class, transportation and habitatΩ☆ional saw the highest average rate i↑♣ €ncreases at 9% and 8.25% respectively, Marke↑>÷tScout said.Large ac≈$♥✔counts – those with $250,001 to $↑Ω♠δ1 million in premium – saw a rate hike of 5Ωα.5% in the fourth quarter, as did jum↑ >bo accounts, which have mor£©e than $1 million in premium≥×↓. Small accounts – those with up tδ₽o $25,000 in premium – were up 5%,  ♣while medium accounts – those with $25,001 to $25≈× 0,000 in premium – we'ΩΩre up 4.5%.The “steady trend”  ‍♦of upward rates reflects insurers’ plans toδ↓§ continue increasing price£★¥♦s across all lines except for ♦₹←↑workers compensation, MarketScout ₹ δsaid.Organizer:China Insurance Digita©γl & AI Developme↔•σnt 2020Web:http://en.zenseegroup ♣.com/p/560573/Contact:Ann 021-65650305

From :insurancejournalIt was a relativ αely quiet year for the Southeast in terms of ma÷ jor catastrophes compared with 2018 when →★Hurricane’s Michael and Florence caused majoφ↕r damage in the region. This year,&n ​αbsp;Hurricane Dorian sideswiped the South∑§×east coast and Ω"±made landfall on the Outer Banks of North Car®§olina but most of the area was spa₩π♠♣red. Still, Aon said economαλ$ic damage in the U.S. and Canada&§"<↓nbsp;was poised to approach a combin₹✔ed $1.5 billion.Florida spent the yea∑≠"r recovering from Hurr↔↕δicane Michael, which was upgraded to a★£Ω¶ Category 5 storm by NOAA in April. F$‍lorida officials have repeatλσ&™edly called on the ins>λ$®urance industry to speed up the recovery ☆ process, with nearly 12% of claims still ope✘✔n a year after the s&<≥γtorm hit.Organizer:C Ω"‌hina Insurance Digital & AI Developm∏γent 2020Web:http://en.zenseegroup.com/p/56057÷♠σ←3/Contact:Ann 021-65650305

From:businessinsuranceeinsurance renewal​₹s at Jan. 1, 2020, mainly saw si≤φngle-digit increases, with some exceptions‍®, according to reports by reinsura β&nce brokers released Thursday.Wi↔•€llis Re, the reinsuran♣"±§ce brokerage of WillisΩγ¥ Towers Watson PLC, and Guy Ca≥λ☆rpenter & Co. LLC, a un'★®±it of Marsh & McLenna¥<± n Cos. Inc. both reported that ye₩♥ar-end reinsurance renewals ₽₽ varied by account and region, £γ¶×but the retrocessional reinsurance w™>↓♠as under pressure.Rateβ←s on line for property catas↓↔trophe reinsurance progr₩β★§ams remained stable and property per £©•risk pricing was driven by in≈✔"dividual program performance, the Willis ♠♦report said.Although some Lloyd’s of Lo ♥ndon syndicates took firm positions on rate¥® increases and the London market authori♥§∑zed capacity decreased, that capactiy was ↔₽replaced by new capital and a strong su<Ω ₩pply from other marke¥∞∏‍ts, Willis Re said.U.S. loss-free accou™‍↓♦nts renewed at flat to₽♠↓ up 10% while those with losses saw increas↔♦™es of 10% to 50%, the↑  ↓ Willis Re report sai☆§d, which was among the largest inc•®₽reases. Property catastrophe accounts witφ<≈φhout losses renewed at flat to up 5%, while lδ  ♦oss hit accounts were up 10% to 20%, Will £is Re said.According to the Guy Car☆σ→penter report, the brokerage’s global property '&σcatastrophe rate on line index rose 5% in 2≤≥±019.According to the Willis ≤♣Re report, other lar↑≠‍ge increases were seen in✘<&↓ Central and Eastern Europe, wαλhere property programs with losses saw increases​‍ of 5% to 20%, and Canada, where such accou₽δ&↕nts renewed up 10% to₩ δ 40%.Most other regions and countries saw prope•  βrty increases in the single or low double digi↓↓π<ts, the report said.The Jan. 1£× renewals saw some “difficult” negotiatγ∏ ions, according to aβ¶ letter in the report from James Kent,→π ↔ global CEO, Willis Re.The Guy C​©♥arpenter report said the ≈'"€reinsurance market was “asymmetrical,”♦δ" adding “this is certainly not a one-siz ₽✔e-fits-all market” and while overall cap∑✘↓acity remained adequate, “allocat∏σed capacity tightened notab₽♦ly in stressed classes.”Dedicat©♥₹ed reinsurance capital rose §↓≥✔2% in 2019 and the year saw apprγ₽∞oximately $60 billion in g∑σλδlobal insured catastr €βΩophe losses, according to Guy Carpenter, which λ was significantly lower th←₹♥an 2017 and 2018.Alternative capital, how♣↕ever, contracted by approximately 7% perc©αent “as investors were more cautioβ↓us with new investmen‌∞←ts after assessing market€₩ε dynamics and pricing✔ ₽ adequacy,” Guy Carpenter said.The retroce δ™ssion market “was ch≠α→allenged … by trapped cγ♠apital, a lack of new capital and continued redem'& ✔ptions from third-party capital provide↓←×rs,” a statement issued with the Guy Carpenter re∏♠port said.However, signifiσ≠←cant retrocession providers re‍≠turned to the market in the past two ÷™∏weeks, Willis Re said.Organizer:China Insurance®✘₹ Digital & AI Development 20♦∞20Web:http://en.zenseegroup.com/p/56057ε &3/Contact:Ann 021-65650305

Major information technology compa$←nies in India are runnin♠±←g the risk of termination of the₩≤★ir $1 billion contracts following Boeing €'Co.’s decision to halt the production o✘ f its 737 Max jets, MoneyControl reported cit®σing the Business Standa↕•rd. Companies like Tata Consultan≠∑©cy Services Ltd., Infosys Ltd., HCL Techn≤δologies Ltd., Cyient Ltd. and L&T Techn→₩§ology Services Ltd. h​¥‍≠ave outsourcing contracts with Boeing or its supp$σliers and Boeing’s jet crisis is expecte£§d to affect these IT companies in ≠☆the short run.From:businessinsuranceOrgani♣♣★zer:China Insurance Digital & AI Development<♣σ$ 2020Web:http://en.zenseegroup.com/p/560573/Co​σα®ntact:Ann 021-65650305

France-based eyewear maker Essilor Inteσ€&<rnational S.A. has discovered fra∞Ωudulent activities at one of its factories in Tha®>iland that could cause €190 m ≤§illion ($213 million) in financial losses §₽×to the company, The Irish Times reporte€γd citing Reuters. The company has filed c∞ omplaints in Thailand and has fired a >♥ll the involved employees. It hopes to reλ✔∑™cover the losses from frozen ba≥♦® nk accounts, insurance and↕"← lawsuits.Organizer:China Insurance Digital &a≠₹↔mp; AI Development 2020Web:http://en.zenseegroupα∏₹$.com/p/560573/Contact:Ann 021-65650305

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